Reverse Transcription Loop-Mediated Isothermal Amplification Assay-Based Infection Control Strategies for COVID-19 in a Hospital Under the State of Emergency in Tokyo, Japan in Spring 2020

Studies describing reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay-based infection control strategies (LAMP-based ICSs) for coronavirus disease 2019 (COVID-19) are limited. We reviewed the medical records of cases in which RT-LAMP was performed. Standard ICSs and LAMP-based were implemented during study period. The intended to impose longer periods precautions (ICPs) specific patients, such as those with a history exposure COVID-19 patients and/or bilateral ground glass opacities (bGGO) on chest computed tomography (CT). Of 212 included 13 confirmed diagnostic cohort, (P <0.0001) CT bGGO = 0.0022) identified significant predictors COVID-19. In 173 hospitalized results first negative, duration ICPs significantly high clinical index suspicion than remaining 0.00046 P 0.0067, respectively). Additionally, no indicating nosocomial spread occurred Establishing comprehensive system that combines rational standard might be useful preventing spread.